Twenty-three others were injured, some of whom are now in critical condition, Minya Gov. Essam El-Bedewy told Egyptian satellite channel ONTV.
Men, women and children are among the dead and injured, officials said.
The exact location of Friday’s airstrikes was unclear but Nile TV reported that Egypt has targeted terrorists in the Sinai Peninsula and on the border with Libya.
In a statement Friday, President Donald Trump said the “merciless slaughter of Christians in Egypt tears at our hearts and grieves our souls.”
“Wherever innocent blood is spilled, a wound is inflicted upon humanity,” the statement said. “But this attack also steels our resolve to bring nations together for the righteous purpose of crushing the evil organizations of terror, and exposing their depraved, twisted, and thuggish ideology.”
The attack comes as the country is still under a three-month state of emergency period following twin attacks on Coptic churches on Palm Sunday last month that killed dozens of people. ISIS claimed responsibility for those attacks.
Bodies lie in the desert after the bus attack on Coptic Christians near Minya in Egypt on Thursday.